版本1.19.1 *的更改我们遵守上游依赖性的更改:PMCMR被PMCMRPLU替换,并连续poSthoc.kruskal.nemenyi.test.default()替换为kwallpairsnemenyitest()()。同样,在包装说明中,作者和维护者的语法适合当前的BioCcheck要求。================================ CHANGES IN VERSION 1.17.2 * We provide a new function LCD_extractCohort_callPerPID() which also belongs对LCD家族并在范围内进行特征的检测,但仅使用在范围内呼叫中确定的签名来重新运行对暴露的实际计算。OVALL包装器功能LCD_COMPLEX_CUTOFF_COMBIND()现在还调用新功能,并将结果存储在返回列表中,并带有项目名称dractrion_callperpid =====================================================================版本1.17.1的更改=======函数的输入参数的最小值lcd_complex_cutoff_perpid(),lcd_complex_cutoff_consensus()和lcd_complex_cutoff_combined()。如果样本的突变少于此截止,则会发出警告。默认情况下,该值设置为25,可能是分析SNV突变签名的好选择。为了分析indel突变签名,一个更好的选择是20。==============================3这是经过几次重要更改后的稳定版本。*可以计算出暴露于突变特征的95%置信区间 *支持PCAWG突变签名的分析,无论是PCAWG SNV和PCAWG SNV和PCAWG签名,Vignettes已实质性更改: * *新的小插曲已为新功能置信区间编写了新功能间隔。 and Indel signatures * new vignettes were added for features already present in the package before, especially the optimal signature-specific cutoffs * the topic of stratifiec analyses of mutational signatures was taken out of the main vignette and now is described in a vignette on its own. ================================ CHANGES IN VERSION 0.99.0 + first version to be submitted to Bioconductor