## ---- foo，cache = false，include = false，echo = false = false ----库（qvalue）选项（keep.source = true，width = 48）foo <-packageScription（“ qvalue”）##----citingqvalue, eval=FALSE----------------- # citation("qvalue") ## ----help_qvalue---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------库（Qvalue）数据（Hedenfalk）PVALUE <-Hedenfalk $ p qobj <-qvalue（p = pvalues）## --------------------------------------------------------------------------------------------库（Qvalue）数据（Hedenfalk）obs_stats <-hedenfalk $ stat null_stats <-hedenfalk $ stat00pvalues <-emppvals（stat = obs_stats，stat0 = null_stats）qobj <-qvalue（p = pvalues）## --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.-------- QVALUE <-QOBJ $ QVALUES PI0 <-QOBJ $ PI0 lfdr <-QOBJ $ LFDR ## ---- QUICT_SUMVIZ，eart eval = false = false ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------＃summary（qobj）＃hist（qobj）＃plot（qobj）## ------------------------------------------------------------------------------------------------------------------数据（hedenfalk）名称（Hedenfalk）## ---- obsnullstat，deverson =“ load_qvalue” ------- null_stats <-hedenfalk $ stat0 obs_stats <- hedenfalk$stat pvalues <- empPvals(stat = obs_stats, stat0 = null_stats, pool = FALSE) ## ----pvalue_hist2, dependson=c("load_qvalue", "quick_p"), fig.height=3，图width = 5 ---- hist（Hedenfalk $ p，nclass = 20）## ----------------------------------------------------------------------------，图Width = 5 ---- set.seed（478）p2 = c（hedenfalk $ p，（runif（450，min = 0.7，max = 1））^（0.33））) hist(somethingsWrong$p, nclass=20, main="Problematic p-values", xlab="intentionally bad, simulated p-values") ## ----run_qvalue, dependson="load_qvalue"------ qobj <- qvalue(p = hedenfalk$p) ## ----outNames, dependson="run_qvalue"--------- names(qobj) ## ----summary_qvalue, dependson="run_qvalue"---- summary(qobj) ## ----pi0, dependson="run_qvalue"-------------- pi0 <- qobj$pi0 ## ----pi0est,dependson="load_qvalue"---------- pi0 <- pi0est(p = hedenfalk$p, lambda = seq(0.1, 0.9, 0.1), pi0.method = "smoother" ) names(pi0) #＃------- QVALUE_EXT，DIDERSON =“ RUN_QVALUE”，无花果。## ---- fdrlevel，divedson =“ run_qvalue”，eval = false = false ----＃qobj_fdrlevel <-qvalue（p = hedenfalk $ p，fdr.level = 0.1）＃qobj $，divedson =“ run_qvalue” ------------------------------------------------------------------------------------------------------------------------------- lfdr(p = hedenfalk$p) ## ----plot_qobj, dependson=c("load_qvalue", "run_qvalue"), fig.width='\textwidth'---- plot(qobj) ## ----hist_qobj, dependson=c("load_qvalue", "run_qvalue"), fig.width='\textwidth'---- hist(qobj)